Comparison of two strategies for the management of postoperative recurrence in Crohn's disease patients with one clinical risk factor: A multicentre IG-IBD study.

ABSTRACT:

Background

The management of postoperative recurrence (POR) in Crohn's disease (CD) after ileo-colonic resection is a highly debated topic. Prophylactic immunosuppression after surgery is currently recommended in the presence of at least one clinical risk factor.

Objective

Our aim was to determine whether early immunosuppression can be avoided and guided by endoscopy in CD patients with only one risk factor.

Methods

CD patients with only one risk factor for POR, including previous intestinal resection, extensive small intestine resection (>50 cm), fistulising phenotype, history of perianal disease, and active smoking, were retrospectively included. Two groups were formed based on whether immunosuppression was started immediately after surgery ("prophylaxis group") or

SUBMITTER: Dragoni G 

PROVIDER: S-EPMC10083469 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature