25-hydroxyvitamin D level is associated with greater grip strength across adult life span: a population-based cohort study.

ABSTRACT:

Objective

Maintaining muscle function throughout life is critical for healthy ageing. Although in vitro studies consistently indicate beneficial effects of 25-hydroxyvitamin D (25-OHD) on muscle function, findings from population-based studies remain inconclusive. We therefore aimed to examine the association between 25-OHD concentration and handgrip strength across a wide age range and assess potential modifying effects of age, sex and season.

Methods

We analysed cross-sectional baseline data of 2576 eligible participants out of the first 3000 participants (recruited from March 2016 to March 2019) of the Rhineland Study, a community-based cohort study in Bonn, Germany. Multivariate linear regression models were used to assess the relation between 25-OHD levels and grip stre

SUBMITTER: Fox FAU 

PROVIDER: S-EPMC10083672 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature