Statins for extension of disability-free survival and primary prevention of cardiovascular events among older people: protocol for a randomised controlled trial in primary care (STAREE trial).

ABSTRACT:

Introduction

The world is undergoing a demographic transition to an older population. Preventive healthcare has reduced the burden of chronic illness at younger ages but there is limited evidence that these advances can improve health at older ages. Statins are one class of drug with the potential to prevent or delay the onset of several causes of incapacity in older age, particularly major cardiovascular disease (CVD). This paper presents the protocol for the STAtins in Reducing Events in the Elderly (STAREE) trial, a randomised double-blind placebo-controlled trial examining the effects of statins in community dwelling older people without CVD, diabetes or dementia.

Methods and analysis

We will conduct a double-blind, randomised placebo-controlled trial among people aged 7

SUBMITTER: Zoungas S 

PROVIDER: S-EPMC10083753 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature