Temporal trends in the incidence of infective endocarditis in patients with a prosthetic heart valve.

ABSTRACT:

Objective

The incidence of infective endocarditis (IE) is increasing, as is the insertion of prosthetic heart valves. We aimed to examine nationwide temporal trends in the incidence of IE in patients with a prosthetic heart valve in Denmark from 1999 to 2018.

Methods

Using the Danish nationwide registries, we identified patients who underwent heart valve implantation (for other reasons than IE) between 1999 and 2018. Crude incidence rates of IE per 1000 person-years (PY) were computed in 2-year intervals. IE incidences were compared using sex-adjusted and age-adjusted incidence rate ratios (IRR) using Poisson regression across calendar periods (1999-2003, 2004-2008, 2009-2013, and 2014-2018).

Results

We identified 26 604 patients with first-time prosthetic valve impla

SUBMITTER: Hadji-Turdeghal K 

PROVIDER: S-EPMC10083846 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature