Mechanism underlying painful radiculopathy in patients with lumbar disc herniation.

ABSTRACT:

Background

Painful lumbar radiculopathy is a neuropathic pain condition, commonly attributed to nerve root inflammation/compression by disc herniation. The present exploratory study searched for associations between pain intensity and inflammatory markers, herniated disc size, infection, psychological factors and pain modulation in patients with confirmed painful lumbar radiculopathy scheduled for spine surgery.

Methods

Prior to surgery, 53 patients underwent the following evaluation: pain intensity measured on a 0-10 numeric rating scale (NRS) and the Short-Form McGill Pain Questionnaire; sensory testing (modified DFNS protocol); pain processing including temporal summation and conditioned pain modulation (CPM); neurological examination; psychological assessment including S

SUBMITTER: Samuelly-Leichtag G 

PROVIDER: S-EPMC10083974 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature