Prevalence of allergic sensitization with vernal keratoconjunctivitis: A systematic review with meta-analyses.

ABSTRACT: To determine the prevalence of allergic sensitization in patients with vernal keratoconjunctivitis (VKC) and to provide an overview of published studies on this topic. We systematically searched 11 literature databases on 24 May 2021, for studies with cross-sectional data on the prevalence of positive allergy tests in patients with VKC. Our main outcome of interest was the prevalence of allergic sensitization and the allergens involved. Prevalence meta-analyses were made to provide summary estimates. We identified 33 eligible studies for qualitative review with 2122 patients with VKC. Studies were predominantly based on patients seen in ophthalmology clinics. Overall, studies reported that the most prevalent positive allergen tests were the inhaled allergens house dust mites and pollen. Tw

SUBMITTER: Rasmussen MLR 

PROVIDER: S-EPMC10084059 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature