Preoperative medical treatments and surgical approaches for acromegaly: A systematic review.

ABSTRACT:

Objective

Acromegaly is a condition characterized by an overproduction of growth hormone which infers high morbidity and mortality if left untreated. The objective of this review is to analyse and appraise the current evidence for the generalized use of preoperative medications and the various surgical approaches as described in the literature.

Design

A thorough search from MEDLINE via PubMed, EMBASE, and Cochrane Library has been performed which identified a total of 37 papers.

Conclusion

The preoperative use of somatostatin receptor agonists (SAs) in acromegaly is a controversial topic with current guidelines suggesting against their generalized routine use. Most authors noticed an insignificant long-term remission of acromegaly when given SAs compared with nil preo

SUBMITTER: Papaioannou C 

PROVIDER: S-EPMC10084190 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature