The management of neovascular age-related macular degeneration: A systematic literature review of patient-reported outcomes, patient mental health and caregiver burden.

ABSTRACT:

Purpose

The aim of this systematic literature review was to describe patient-reported outcomes, mental health and caregiver burden in patients with neovascular age-related macular degeneration (nAMD) treated with anti-vascular endothelial growth factor (VEGF) agents in routine clinical practice.

Methods

Electronic searches were conducted in Embase and MEDLINE according to pre-defined criteria.

Results

Of 856 records identified, 63 met inclusion criteria. Depression or depressive symptoms were reported in up to 42% of patients with nAMD. Of 25/63 (40%) studies evaluating quality of life (QoL) and using various tools, eight studies reported composite National Eye Institute Visual Functioning Questionnaire scores following anti-VEGF treatment. Of these, seven reported a

SUBMITTER: Gale RP 

PROVIDER: S-EPMC10084380 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature