Observational Study Examining Kidney Transplantation Outcomes Following Donation From Individuals That Died of Drug Toxicity in British Columbia, Canada.

ABSTRACT:

Background

The illicit drug toxicity (overdose) crisis has worsened across Canada, between 2016 and 2021 more than 28 000 individuals have died of drug toxicity. Organ donation from persons who experience drug toxicity death has increased in recent years.

Objective

This study examines whether graft loss after kidney transplantation differed by donor cause of death.

Design

Retrospective cohort.

Setting

Provincial transplant program of British Columbia, Canada.

Patients

Transplant recipients who received kidney transplantation from deceased donors aged 12 to 70 years between 2013 and 2019 (N = 1012).

Measurements

Transplant recipient all cause graft loss (graft loss due to any cause including death) was compared by donor cause of death from drug tox

SUBMITTER: Xie MW 

PROVIDER: S-EPMC10084533 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature