Dynamic Involvement of Striatal NG2-glia in L-DOPA Induced Dyskinesia in Parkinsonian Rats: Effects of Doxycycline.

ABSTRACT:

Summary statement

NG2-glia alters its dynamics in response to L-DOPA-induced dyskinesia. In these animals, striatal NG2-glia density was reduced with cells presenting activated phenotype while doxycycline antidyskinetic therapy promotes a return to NG2-glia cell density and protein to a not activated state.

SUBMITTER: Nascimento GC 

PROVIDER: S-EPMC10084551 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature