The trade-off between COVID-19 and mental diseases burden during a lockdown: Mathematical modeling of control measures.

ABSTRACT:

Background

During the COVID-19 pandemic, many countries used lockdowns as a containment measure. While lockdowns successfully contributed to slowing down the contagion, the related mobility restrictions were reportedly associated with an increased risk of major depressive and anxiety disorders. We aimed to quantify the trade-off between the quality-adjusted life years (QALY) gain due to lower COVID-19 incidence as a result of a lockdown and QALY loss due to lockdown-induced mental disorders.

Methods

We developed an agent-based model of COVID-19 epidemic and coupled mental disorder development in the population of a large city. We used data sources on the places of living, studying and working, public health and census surveys. Modeling of mental disorders was based on diathe

SUBMITTER: Romanyukha AA 

PROVIDER: S-EPMC10084665 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature