Serum copeptin as a predictor of risk of hyponatremia after transurethral prostatectomy.

ABSTRACT:

Background

Transurethral resection of the prostate gland (TURP) frequently leads to the development of dilutional hyponatremia. Copeptin has been established as a surrogate marker of vasopressin and is measured for clinical assessment of various sodium and water disturbances. This study aims to assess the utility of serum concentration of copeptin and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) for prediction of post-TURP alterations of serum sodium concentration.

Methods

Forty-three patients with benign prostatic hyperplasia undergoing TURP were enrolled. Serum sodium and copeptin were measured before the procedure, then 12 hours after its completion. NT-proBNP was assessed at baseline. The total amount of fluids and sodium administered intravenously and

SUBMITTER: Bryc-Walczak K 

PROVIDER: S-EPMC10085729 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature