Microbiome-based enrichment pattern mining has enabled a deeper understanding of the biome-species-function relationship.

ABSTRACT: Microbes live in diverse habitats (i.e. biomes), yet their species and genes were biome-specific, forming enrichment patterns. These enrichment patterns have mirrored the biome-species-function relationship, which is shaped by ecological and evolutionary principles. However, a grand picture of these enrichment patterns, as well as the roles of external and internal factors in driving these enrichment patterns, remain largely unexamined. In this work, we have examined the enrichment patterns based on 1705 microbiome samples from four representative biomes (Engineered, Gut, Freshwater, and Soil). Moreover, an "enrichment sphere" model was constructed to elucidate the regulatory principles behind these patterns. The driving factors for this model were revealed based on two case studies: (1) T

SUBMITTER: Yang P 

PROVIDER: S-EPMC10085995 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature