Evaluation of outcome of chemotherapy for breast cancer patients older than 70 years: A SEER-based study

ABSTRACT:

Background

With the aging of the population, the number of elderly breast cancer cases has increased. However, there is a lack of effective randomized clinical trial data to support whether elderly patients should receive chemotherapy. Our goal was to observe the relationship between chemotherapy and breast cancer-specific survival (BCSS) in elderly breast cancer patients and to identify those who could benefit from chemotherapy.

Methods

We collected the data of patients who were diagnosed with invasive ductal carcinoma and older than 70 years in the SEER database from 1995 to 2016. The independent predictors of BCSS were identified by Cox regression analysis. Propensity score matching (PSM) and inverse probability of treatment weighting (IPTW) were performed to eliminate

SUBMITTER:  

PROVIDER: S-EPMC10086342 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature