Artificial intelligence annotated clinical-pathologic risk model to predict outcomes of advanced gastric cancer.

ABSTRACT:

Background

Gastric cancer with synchronous distant metastases indicates a dismal prognosis. The success in survival improvement mainly relies on our ability to predict the potential benefit of a therapy. Our objective is to develop an artificial intelligence annotated clinical-pathologic risk model to predict its outcomes.

Methods

In participants (n=47553) with gastric cancer of the surveillance, epidemiology, and end results program, we selected patients with distant metastases at first diagnosis, complete clinical-pathologic data and follow-up information. Patients were randomly divided into the training and test cohort at 7:3 ratio. 93 patients with advanced gastric cancer from six other cancer centers were collected as the external validation cohort. Multivariable analys

SUBMITTER: Chen Y 

PROVIDER: S-EPMC10086433 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature