Ethylene oxide emissions and incident breast cancer and non-Hodgkin lymphoma in a US cohort.

ABSTRACT:

Background

Ethylene oxide (EtO) is a carcinogenic gas used in chemical production and to sterilize medical equipment that has been linked to risk of breast and lymphohematopoietic cancers in a small number of occupational studies. We investigated the relationship between environmental EtO exposure and risk of these cancers.

Methods

Using the US Environmental Protection Agency's Toxics Release Inventory, we estimated historical exposures for National Institutes of Health-AARP Diet and Health Study participants enrolled in 1995-1996. We constructed 2 metrics at 3, 5, and 10 km: 1) distance between residences and EtO-emitting facilities, weighted by the proportion of time the home was downwind of each facility, and 2) distance-weighted, wind direction-adjusted average airborne

SUBMITTER: Jones RR 

PROVIDER: S-EPMC10086621 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature