Characteristics and associations of microbial community in the eye, anterior nares, and oropharynx of healthy adults: eye-nose microbiota transmission.

ABSTRACT:

Purpose

We compared the microbial communities of the eye, anterior nares (ANs) and oropharynx (OP) of healthy adults to provide a basic understanding of the microbial associations among the three sites.

Methods

The name of the registry of our prospective study was "Study on the diversity of microbial flora in the eye, nose and oropharynx of healthy people". The trial number is ChiCTR2300067724 (https://www.chictr.org.cn/index.aspx). Swabs were collected from the eye, ANs and OP of 48 healthy adult participants for 16S rRNA gene amplicon sequencing. The bacterial community profiles and their functional associations were compared among the three sites.

Results

At a phylum level, the basic bacterial compositions in the eye and ANs were generally similar, and the predomin

SUBMITTER: Zhang X 

PROVIDER: S-EPMC10086891 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature