ClevRvis: visualization techniques for clonal evolution.

ABSTRACT:

Background

A thorough analysis of clonal evolution commonly requires integration of diverse sources of data (e.g., karyotyping, next-generation sequencing, and clinical information). Subsequent to actual reconstruction of clonal evolution, detailed analysis and interpretation of the results are essential. Often, however, only few tumor samples per patient are available. Thus, information on clonal development and therapy effect may be incomplete. Furthermore, analysis of biallelic events-considered of high relevance with respect to disease course-can commonly only be realized by time-consuming analysis of the raw results and even raw sequencing data.

Results

We developed clevRvis, an R/Bioconductor package providing an extensive set of visualization techniques for clonal evo

SUBMITTER: Sandmann S 

PROVIDER: S-EPMC10087014 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature