Massive blood transfusion following older adult trauma: The effect of blood ratios on mortality.

ABSTRACT:

Background

Massive blood transfusion (MBT) following older adult trauma poses unique challenges. Despite extensive evidence on optimal resuscitative strategies in the younger adult patients, there is limited research in the older adult population.

Methods

We used the Trauma Quality Improvement Program (TQIP) database from 2013 to 2017 to identify all patients over 65 years old who received a MBT. We stratified our population into six fresh-frozen plasma:packed red blood cell (FFP:pRBC) ratio cohorts (1:1, 1:2, 1:3, 1:4, 1:5, 1:6+). Our primary outcomes were 24-h and 30-day mortality. We constructed multivariable regression models with 1:1 group as the baseline and adjusted for confounders to estimate the independent effect of blood ratios on mortality.

Results

A total

SUBMITTER: Hohle RD 

PROVIDER: S-EPMC10087121 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature