Parental atopy and risk of atopic dermatitis in the first two years of life in the BASELINE birth cohort study.

ABSTRACT:

Background

Atopic dermatitis (AD) has a strong genetic basis. The objective of this study was to assess the association between parental atopy and AD development by 2 years.

Methods

A secondary data analysis of the BASELINE Birth Cohort study was performed (n = 2183). Parental atopy was self-reported at 2 months. Infants were examined for AD by trained health care professionals at 6, 12, and 24 months. Variables extracted from the database related to skin barrier function, early skincare, parental atopy, and AD. Statistical analysis adjusted for potential confounding variables.

Results

Complete data on AD status were available for 1505 children at 6, 12, and 24 months. Prevalence of AD was 18.6% at 6 months, 15.2% at 12 months, and 16.5% at 24 months. Adjusted odds ra

SUBMITTER: O'Connor C 

PROVIDER: S-EPMC10087322 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature