Primary Sjogren syndrome-related peripheral neuropathy: A systematic review and meta-analysis.

ABSTRACT:

Background and purpose

Primary Sjögren syndrome (pSS) is a chronic, systemic, autoimmune disorder characterized by lymphocytic infiltrates of the exocrine organs, leading to sicca symptoms and parotid enlargement. pSS has been linked to various neurological manifestations, including peripheral neuropathy (PN). We aimed to provide a comprehensive analysis of the currently available evidence regarding pSS-related PN.

Methods

A literature search in the PubMed database was performed, and 49 papers were eligible to be included in this systematic review and meta-analysis.

Results

The pooled prevalence of PN in pSS is estimated to be 15.0% (95% confidence interval = 10.7%-20.7%). The mean age of pSS patients at PN diagnosis is 59 years. Among the patients with pSS and PN, 83

SUBMITTER: Liampas A 

PROVIDER: S-EPMC10087501 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature