Treatment of periodontitis and C-reactive protein: A systematic review and meta-analysis of randomized clinical trials.

ABSTRACT:

Background

Systemic inflammation is implicated in the onset and progression of several chronic diseases. Periodontitis is a potential trigger of systemic inflammation.

Purpose

To comprehensively appraise all the evidence on the effects of the treatment of periodontitis on systemic inflammation assessed by serum C-reactive protein (CRP) levels.

Data sources

Six electronic databases were searched up to 10 February 2022 to identify and select articles in English language only.

Study selection

Twenty-six randomized controlled clinical trials reporting changes amongst 2579 participants about CRP levels at 6 months or more after treatment.

Data extraction

Two reviewers independently extracted data and rated the quality of studies. Meta-analyses were performed

SUBMITTER: Luthra S 

PROVIDER: S-EPMC10087558 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature