Therapy decisions after diagnosis of prostate cancer in men with negative prostate MRI.

ABSTRACT:

Background

To investigate the clinical implications of magnetic resonance imaging (MRI) negative prostate cancer (PCa) in a cohort of men undergoing transperineal prostate biopsy.

Methods

We included all men without prior diagnosis of PCa undergoing transperineal template saturation ± fusion-guided targeted biopsy of the prostate between November 2014 and March 2018. Before biopsy, all patients underwent MRI and biopsies were performed irrespective of imaging results. Baseline characteristics, imaging, biopsy results, and follow-up information were retrieved from the patient charts. Patients were classified as either MRI negative (Prostate Imaging Reporting and Data System [PIRADS] ≤ 2) or positive (PIRADS ≥ 3). ISUP grade group 1 was defined as clinically nonsignificant (ns

SUBMITTER: Schmid FA 

PROVIDER: S-EPMC10087805 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature