Current and future applications of liquid biopsy in non-small-cell lung cancer-a narrative review.

ABSTRACT:

Background and objective

Lung cancer remains the leading cause of cancer-related mortality and constitutes a significant societal burden. Recent advancements in targeted therapies and immunotherapy have considerably broadened therapeutic options in lung cancer, particularly in non-small-cell lung cancer (NSCLC). However, these novel methods necessitate sophisticated molecular diagnostics. Liquid biopsy, which refers to the cytological and molecular analysis of cancer markers shed by the tumor into the body fluids, may offer an attractive diagnostic tool at the individual patient level. This approach is particularly relevant for lung cancer, as the anatomical location of tumor lesions frequently makes them inaccessible for tissue biopsy. Apart from minimal invasiveness, the major ad

SUBMITTER: Tomasik B 

PROVIDER: S-EPMC10087994 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature