Clinical risk factors for increased respiratory drive in intubated hypoxemic patients.

ABSTRACT:

Background

There is very limited evidence identifying factors that increase respiratory drive in hypoxemic intubated patients. Most physiological determinants of respiratory drive cannot be directly assessed at the bedside (e.g., neural inputs from chemo- or mechano-receptors), but clinical risk factors commonly measured in intubated patients could be correlated with increased drive. We aimed to identify clinical risk factors independently associated with increased respiratory drive in intubated hypoxemic patients.

Methods

We analyzed the physiological dataset from a multicenter trial on intubated hypoxemic patients on pressure support (PS). Patients with simultaneous assessment of the inspiratory drop in airway pressure at 0.1-s during an occlusion (P_0.1) and ris

SUBMITTER: Spinelli E 

PROVIDER: S-EPMC10088111 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature