Osteoporosis treatment using stem cell-derived exosomes: a systematic review and meta-analysis of preclinical studies.

ABSTRACT:

Background

The increasing incidence of osteoporosis in recent years has aroused widespread public concern; however, existing effective treatments are limited. Therefore, new osteoporosis treatment methods, including stem cell transplantation and exosome therapy, have been proposed and are gaining momentum. Exosomes are considered to have greater potential for clinical application owing to their immunocompatibility. This study summarises the latest evidence demonstrating the efficacy of exosomes in improving bone loss in the treatment of osteoporosis.

Main text

This systematic review and meta-analyses searched PubMed, Embase, and Cochrane Library databases from inception to 26 March 2022 for osteoporosis treatment studies using stem cell-derived exosomes. Six endpoints were s

SUBMITTER: He X 

PROVIDER: S-EPMC10088147 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature