The effect of intensive statin therapy in non-symptomatic intracranial arteries: The STAMINA-MRI sub-study.

ABSTRACT:

Background and aims

Pleiotropic effects of statins result in the stabilization of symptomatic intracranial arterial plaque. However, little is known about the effect of statins in non-symptomatic cerebral arteries. We hypothesized that intensive statin therapy could produce a change in the non-symptomatic cerebral arteries.

Methods

This is a sub-study of a prospective observational study under the title of "Intensive Statin Treatment in Acute Ischemic Stroke Patients with Intracranial Atherosclerosis: a High-Resolution Magnetic Resonance Imaging (HR-MRI) study." Patients with statin-naive acute ischemic stroke who had symptomatic intracranial artery stenosis (above 50%) were recruited for this study. HR-MRI was performed to assess the patients' cerebral arterial status befor

SUBMITTER: Sim JE 

PROVIDER: S-EPMC10088516 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature