Convex optimization for maximizing the degradation efficiency of chloroquine in a flow-by electrochemical reactor.

ABSTRACT: The degradation efficiency of chloroquine phosphate (CQ), an anti-COVID-19 drug, was investigated in a flow-by electrochemical reactor (FBER) provided with two boron-doped diamond (BDD) electrodes (as cathode and anode) under batch recirculation mode. A central composite rotatable design (CCRD) was run down to model and assess the influence of initial pH in an interval of 3.71 to 11.28, the current density in an interval of 34.32 to 185.68 mA cm^-2, and liquid volumetric flow rate in an interval of 0.58 to 1.42 L min^-1, and conduct the convex optimization to obtain the maximum degradation efficiency. Experimental results were modeled through a second-order polynomial equation having a determination coefficient (R²) of 0.9705 with a variance coefficien

SUBMITTER: Regalado-Mendez A 

PROVIDER: S-EPMC10088624 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature