Exploring relationships between autistic traits and body temperature, circadian rhythms, and age.

ABSTRACT: The number of clinical diagnoses of autism spectrum disorder (ASD) is increasing annually. Interestingly, the human body temperature has also been reported to gradually decrease over the decades. An imbalance in the activation of the excitatory and inhibitory neurons is assumed to be involved in the pathogenesis of ASD. Neurophysiological evidence showed that brain activity decreases as cortical temperature increases, suggesting that an increase in brain temperature enhances the inhibitory neural mechanisms. Behavioral characteristics specific to clinical ASD were observed to be moderated when people with the diagnoses had a fever. To explore the possible relationship between ASD and body temperature in the general population, we conducted a survey study using a large population-based samp

SUBMITTER: Hidaka S 

PROVIDER: S-EPMC10088634 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature