Revisiting Exclusion of Prior Cancer in Clinical Trials of Male Breast Cancer.

ABSTRACT: Background: Eligibility criteria for cancer clinical trials present challenges to enrollment. Many trials exclude patients with a prior cancer. This common practice may be especially detrimental to trials of rare cancers, such as male breast cancer, that struggle to accrue adequate numbers of participants. Objectives: To estimate prevalence of prior cancer among men newly diagnosed with breast cancer and describe characteristics of men with prior cancer compared to those without. Methods: We identified men diagnosed with breast cancer between 2011-2015 using population-based data from National Cancer Institute's Surveillance, Epidemiology, and End Results program of cancer registries. We used sequence number and diagnosis year to identify cancers diagnosed prior to bre

SUBMITTER: Rathod A 

PROVIDER: S-EPMC10088891 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature