Standing genetic variation and chromosome differences drove rapid ecotype formation in a major malaria mosquito.

ABSTRACT: Species distributed across heterogeneous environments often evolve locally adapted ecotypes, but understanding of the genetic mechanisms involved in their formation and maintenance in the face of gene flow is incomplete. In Burkina Faso, the major African malaria mosquito Anopheles funestus comprises two strictly sympatric and morphologically indistinguishable yet karyotypically differentiated forms reported to differ in ecology and behavior. However, knowledge of the genetic basis and environmental determinants of An. funestus diversification was impeded by lack of modern genomic resources. Here, we applied deep whole-genome sequencing and analysis to test the hypothesis that these two forms are ecotypes differentially adapted to breeding in natural swamps versus irrigated r

SUBMITTER: Small ST 

PROVIDER: S-EPMC10089221 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature