Clinical features suggesting renal hypouricemia as the cause of acute kidney injury: a case report and review of the literature.

ABSTRACT: Hypouricemia is defined as a level of serum uric acid below 2 mg/dl. Renal hypouricemia is related to genetic defects of the uric acid tubular transporters urate transporter 1 and glucose transporter 9. Patients with renal hypouricemia can be completely asymptomatic or can develop uric acid kidney stones or acute kidney injury, particularly after exercise. Renal hypouricemia is especially challenging to diagnose in patients with acute kidney injury, due to the nonspecific clinical, hematochemical and histological features. No common features are reported in the literature that could help clinicians identify renal hypouricemia-acute kidney injury. Currently available guidelines on diagnosis and management of renal hypouricemia provide limited support in defining clues for the differential d

SUBMITTER: Mazzierli T 

PROVIDER: S-EPMC10089983 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature