Early detection and serial monitoring during chemotherapy-radiation therapy: Using T1 and T2 mapping cardiac magnetic resonance imaging.

ABSTRACT:

Purpose

To confirm the ability of native T1 and T2 values in detecting and monitoring early myocardial injuries of chest radiotherapy in neoplasm patients.

Materials and methods

Fifteen participants received non-anthracycline chemotherapy and chest radiotherapy, and 30 age/gender-matched controls were enrolled in this prospective study. Cardiac magnetic resonance scans were performed within 2 days, 3 months, and 6 months after chest radiotherapy. Myocardial native T1 and T2 values were measured in irradiated and nonirradiated areas. Meanwhile, the parameters of left ventricular function and left ventricular myocardial strain were obtained.

Results

There were no significant differences in left ventricular function, native T1, T2, and strain between patients and control

SUBMITTER: Tian Y 

PROVIDER: S-EPMC10090395 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature