Virulence capacity of different Aspergillus species from invasive pulmonary aspergillosis.

ABSTRACT:

Introduction

The opportunistic filamentous fungus Aspergillus causes invasive pulmonary aspergillosis (IPA) that often turns into a fatal infection in immunocompromised hosts. However, the virulence capacity of different Aspergillus species and host inflammation induced by different species in IPA are not well understood.

Methods

In the present study, host inflammation, antimicrobial susceptibilities and virulence were compared among clinical Aspergillus strains isolated from IPA patients.

Results

A total of 46 strains were isolated from 45 patients with the invasive infection, of which 35 patients were diagnosed as IPA. Aspergillus flavus was the dominant etiological agent appearing in 25 cases (54.3%). We found that the CRP level and leuk

SUBMITTER: Chen B 

PROVIDER: S-EPMC10090689 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature