Changes in resident microbiota associated with mice susceptibility or resistance to the intestinal trematode Echinostoma caproni.

ABSTRACT: Echinostoma caproni (Trematoda: Echinostomatidae) is an intestinal trematode with no tissue phases in the definitive host that has been extensively used as an experimental model to study the factors that determine resistance against intestinal helminths. In E. caproni infections in mice, interleukin-25 (IL-25) plays a critical role and it is required for the resistance to infection. However, little is known on the factors that determine its production. Primary E. caproni infection in mice is characterized by the development of chronic infections and elevated worm recovery, in relation to a local Th1 response with elevated production of interferon-γ. However, partial resistance against secondary E. caproni infections in ICR (Institute of Cancer Research) m

SUBMITTER: Alvarez-Izquierdo M 

PROVIDER: S-EPMC10090781 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature