Different antibody responses between liver and kidney transplant recipients elicited by third doses of COVID-19 mRNA vaccines.

ABSTRACT:

Background

Solid organ transplant recipients exhibit decreased antibody responses, mainly due to their weakened immune systems. However, data are limited on antibody responses after the primary series of coronavirus disease 2019 (COVID-19) vaccines among recipients of various solid organ transplant types. Thus, we compared the antibody responses after three COVID-19 vaccine doses between liver transplant (LT) and kidney transplant (KT) recipients.

Methods

We prospectively enrolled solid organ transplant recipients who received three COVID-19 vaccine doses from June 2021 to February 2022 and measured S1-specific immunoglobulin G antibodies using an enzyme-linked immunosorbent assay.

Results

Seventy-six LT and 17 KT recipients were included in the final analysis. KT rec

SUBMITTER: Lim SY 

PROVIDER: S-EPMC10090824 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature