Serum copeptin is associated with major complications of liver cirrhosis and spontaneous bacterial peritonitis.

ABSTRACT:

Aim of the study

We aimed to investigate the possible association between serum copeptin and complications of liver cirrhosis, including its potential role as a stress biomarker in spontaneous bacterial peritonitis (SBP).

Material and methods

This cross-sectional study included 89 cirrhotic ascitic patients (37 with SBP and 52 without SBP) admitted to Sohag University Hospitals, Egypt, between June 2021 and February 2022. Serum copeptin was measured in all patients, and its association with SBP and other complications of liver cirrhosis was investigated.

Results

Serum copeptin was significantly elevated in patients with SBP compared to those without SBP (p = 0.032) and significantly correlated with ascitic fluid study parameters, systemic inflammatory markers,

SUBMITTER: Abudeif A 

PROVIDER: S-EPMC10090990 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature