Prediction of pelvic lymph node metastases and PSMA PET positive pelvic lymph nodes with multiparametric MRI and clinical information in primary staging of prostate cancer.

ABSTRACT:

Purpose

To compare the accuracy of multiparametric MRI (mpMRI), ⁶⁸Ga-PSMA PET and the Briganti 2019 nomogram in the prediction of metastatic pelvic lymph nodes (PLN) in prostate cancer, to assess the accuracy of mpMRI and the Briganti nomogram in prediction of PET positive PLN and to investigate the added value of quantitative mpMRI parameters to the Briganti nomogram.

Method

This retrospective IRB-approved study included 41 patients with prostate cancer undergoing mpMRI and ⁶⁸Ga-PSMA PET/CT or MR prior to prostatectomy and pelvic lymph node dissection. A board-certified radiologist assessed the index lesion on diffusion-weighted (Apparent Diffusion Coefficient, ADC; mean/volume), T2-weighted (capsular contact length, lesion volume/maximal diameters) an

SUBMITTER: Hotker AM 

PROVIDER: S-EPMC10091040 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature