Interregional phase-amplitude coupling between theta rhythm in the nucleus tractus solitarius and high-frequency oscillations in the hippocampus during REM sleep in rats.

ABSTRACT: Cross-frequency coupling (CFC) between theta and high-frequency oscillations (HFOs) is predominant during active wakefulness, REM sleep and behavioral and learning tasks in rodent hippocampus. Evidence suggests that these state-dependent CFCs are linked to spatial navigation and memory consolidation processes. CFC studies currently include only the cortical and subcortical structures. To our knowledge, the study of nucleus tractus solitarius (NTS)-cortical structure CFC is still lacking. Here we investigate CFC in simultaneous local field potential recordings from hippocampal CA1 and the NTS during behavioral states in freely moving rats. We found a significant increase in theta (6-8 Hz)-HFO (120-160 Hz) coupling both within the hippocampus and between NTS theta and hippocampal HFOs during

SUBMITTER: Atiwiwat D 

PROVIDER: S-EPMC10091087 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature