NtLink: A Toolkit for De Novo Genome Assembly Scaffolding and Mapping Using Long Reads.

ABSTRACT: With the increasing affordability and accessibility of genome sequencing data, de novo genome assembly is an important first step to a wide variety of downstream studies and analyses. Therefore, bioinformatics tools that enable the generation of high-quality genome assemblies in a computationally efficient manner are essential. Recent developments in long-read sequencing technologies have greatly benefited genome assembly work, including scaffolding, by providing long-range evidence that can aid in resolving the challenging repetitive regions of complex genomes. ntLink is a flexible and resource-efficient genome scaffolding tool that utilizes long-read sequencing data to improve upon draft genome assemblies built from any sequencing technologies, including the same long reads. Instead of u

SUBMITTER: Coombe L 

PROVIDER: S-EPMC10091225 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature