Towards an active droplet-based microfluidic platform for programmable fluid handling.

ABSTRACT: Droplet-based microfluidic systems have emerged as powerful alternatives to conventional high throughput screening platforms, due to their operational flexibility, high-throughput nature and ability to efficiently process small fluid volumes. However, the challenges associated with performing bespoke operations on user-defined droplets often limit their utility in screening applications that involve complex workflows. To this end, the marriage of droplet- and valve-based microfluidic technologies offers the prospect of balancing the controllability of droplet manipulations and analytical throughput. In this spirit, we present a microfluidic platform that combines the capabilities of integrated microvalve technology with droplet-based sample compartmentalization to realize a highly adaptabl

SUBMITTER: Cao X 

PROVIDER: S-EPMC10091362 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature