Antimicrobial activities and phylogenetic study of Erythrina senegalensis DC (Fabaceae) seed lectin.

ABSTRACT: Erythrina senegalensis (Fabaceae) have been traditionally used in the treatment of microbial ailments, and the specific agent mediating its efficacy has been investigated in several studies. In this study, the antimicrobial activity of purified E. senegalensis lectin (ESL) was analyzed. The phylogenetic relationship of the gene encoding lectin with other legume lectins was also established to investigate their evolutionary relationship via comparative genomics. Antimicrobial activity of ESL against selected pathogenic bacteria and fungi isolates was evaluated by the agar well diffusion method, using fluconazole (1 mg/ml) and streptomycin (1 mg/ml) as positive controls for fungi and bacteria sensitivity, respectively. Potent antimicrobial activity of ESL against Erwinia car

SUBMITTER: Enoma S 

PROVIDER: S-EPMC10091453 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature