Fit for Purpose Assessment: A New Direction for IACUCs.

ABSTRACT: The organization and function of the institutional animal care and use committee (IACUC) is the key component of government regulation and oversight of necessary scientific research using live animals and of AAALAC - International accreditation of animal care and use programs in the United States. The regulations, roles, and responsibilities of IACUCs have evolved since their inception 35 years ago from a limited focus on animal welfare and specific animal procedures to embracing scientific quality, data reproducibility and translation, and animal welfare as inextricably interdependent and critical components of generation of new scientific knowledge and medical treatments. A current challenge for IACUCs is in evaluating whether benefits to be derived (eg, new knowledge or treatments) just

SUBMITTER: Kinter LB 

PROVIDER: S-EPMC10091468 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature