Distinctive kidney function trajectories following left ventricular assist device implantation.

ABSTRACT:

Background

The aim of this study was to assess for distinct kidney function trajectories following left ventricular assist device (LVAD) placement. Cohort studies of LVAD recipients demonstrate that kidney function tends to increase early after LVAD placement, followed by decline and limited sustained improvement. Inter-individual differences in kidney function response may be obscured.

Methods

We identified continuous flow LVAD implantations in US adults (2016-2017) from INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support). Primary outcomes were estimated glomerular filtration rate (eGFR) trajectories pre-implantation to ∼12 months. Latent class mixed models were applied to primary and validation samples. Clinical differences among trajectory group

SUBMITTER: Walther CP 

PROVIDER: S-EPMC10091513 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature