Viral infection and allergy status impact severity of asthma symptoms in children with asthma exacerbations.

ABSTRACT:

Background

Although viral infection is known to be associated with asthma exacerbations, prior research has not identified reliable predictors of acute symptom severity in virus-related asthma exacerbations (VRAEs).

Objective

To determine the effect of asthma control and viral infection on the severity of current illness and evaluate biomarkers related to acute symptoms during asthma exacerbations.

Methods

We prospectively enrolled 120 children with physician-diagnosed asthma and current wheezing who presented to Arkansas Children's Hospital emergency department. The asthma control test (ACT) stratified controlled (ACT > 19) and uncontrolled (ACT ≤ 19) asthma, whereas pediatric respiratory symptom scores evaluated symptoms. Nasopharyngeal swabs were obtained for viral

SUBMITTER: Dinwiddie DL 

PROVIDER: S-EPMC10091837 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature