Characterization of the GU microbiome in women with self-perceived bladder health over the life course.

ABSTRACT:

Background

A variety of factors influence bladder health, including environmental factors, life experiences, biologic foundations, and coexistent medical conditions. A biologically diverse microbial community exists in the urine that is likely influenced by the microbial inhabitants of the vagina. The relationship between the genitourinary (GU) microbiome and self-perceived bladder health is unknown.

Objective

To longitudinally define the GU microbiome in women with self-percieved bladder health sampled across multiple time points over a year.

Study design

Women with no reported lower urinary tract dysfunction or symptoms (LUTS) were recruited from six clinical sites and assessed every 6 weeks for 1 year. Voided urine and vaginal samples were longitudinally collected.

SUBMITTER: Mueller MG 

PROVIDER: S-EPMC10091982 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature