Causes of hypercapnic respiratory failure and associated in-hospital mortality.

ABSTRACT:

Background and objective

Hypercapnic respiratory failure (HRF) can occur due to severe respiratory disease but also because of multiple coexistent causes. There are few data on the prevalence of antecedent causes for HRF and the effect of these causes on prognosis, especially where study inclusion has not been biased with respect to primary diagnosis, interventions received or clinical outcome. We sought to determine the prevalence of pre-specified conditions among patients with HRF and to determine the effect of these causes on in-hospital mortality.

Methods

Cross-sectional study of patients with HRF from 2013 to 2017. Inclusion criteria were PaCO₂  >45 mm Hg and pH ≤7.45. Causes of interest were identified using diagnosis codes from hospital records. We used dir

SUBMITTER: Chung Y 

PROVIDER: S-EPMC10092076 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature