Intestinal ultrasound detects an increased diameter and submucosal layer thickness in the appendix of patients with ulcerative colitis compared to healthy controls - a prospective cohort study.

ABSTRACT:

Background

Increasing evidence suggests that appendicectomy as alternative treatment for ulcerative colitis (UC), especially in patients with histopathological appendiceal inflammation. Intestinal ultrasound (IUS) is a non-invasive diagnostic modality to characterise appendiceal inflammation.

Aims

To assess appendiceal IUS characteristics in UC patients and compare findings to healthy controls (HC).

Methods

In this prospective study, appendiceal IUS was performed in consecutive UC patients with active (A; n = 35) or quiescent (Q; n = 30) disease and in HC (n = 30). Transverse appendiceal diameter (TAD) and additional IUS parameters (bowel wall thickness, submucosal layer thickness and colour Doppler signal) were assessed.

Results

The appendix was visualised in

SUBMITTER: Reijntjes MA 

PROVIDER: S-EPMC10092200 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature