Real-world effectiveness and safety of insulin glargine 300 U/ml in insulin-naive people with type 2 diabetes in the Latin America region: A subgroup analysis of the ATOS.

ABSTRACT:

Aim

To evaluate the real-world effectiveness and safety of insulin glargine 300 U/ml (Gla-300) in achieving glycaemic goals in insulin-naïve people with type 2 diabetes (T2D) in Mexico, Colombia and Peru (Latin America region) in the A Toujeo Observational Study (ATOS).

Materials and methods

ATOS was a multicentre, prospective, 12-month observational study, which included 4422 insulin-naïve adults (age ≥ 18 years) with T2D uncontrolled (HbA1c > 7% and ≤11%) on at least one oral antidiabetic drug (OAD) who initiated Gla-300 treatment as per routine practice. The primary endpoint was the percentage of participants achieving their predefined individualized HbA1c goal at month 6. Key secondary endpoints included change from baseline in HbA1c, fasting plasma glucose (FPG), fastin

SUBMITTER: Vargas-Uricoechea H 

PROVIDER: S-EPMC10092222 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature