Differential Tunneling-Driven and Vibrationally-Induced Reactivity in Isomeric Benzazirines.

ABSTRACT: Quantum mechanical tunneling of heavy-atoms and vibrational excitation chemistry are unconventional and scarcely explored types of reactivity. Once fully understood, they might bring new avenues to conduct chemical transformations, providing access to a new world of molecules or ways of exquisite reaction control. In this context, we present here the discovery of two isomeric benzazirines exhibiting differential tunneling-driven and vibrationally-induced reactivity, which constitute exceptional results for probing into the nature of these phenomena. The isomeric 6-fluoro- and 2-fluoro-4-hydroxy-2H-benzazirines (3-a and 3'-s) were generated in cryogenic krypton matrices by visible-light irradiation of the corresponding triplet nitrene ³ 2-a, which was produced by UV-light irradia

SUBMITTER: Nunes CM 

PROVIDER: S-EPMC10092225 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature